Publications by authors named "Y Lassoued"

Article Synopsis
  • Respiratory syncytial virus (RSV) is a major cause of lower respiratory infections in children, and a new monoclonal antibody, nirsevimab, was introduced in September 2023 to combat RSV.
  • A study was conducted on infants under 12 months old to evaluate the effectiveness of nirsevimab against RSV-bronchiolitis in outpatient settings, involving a comparison between RSV-positive and RSV-negative bronchiolitis patients.
  • The findings showed that nirsevimab reduced the risk of RSV-bronchiolitis by 79.7%, indicating its effectiveness in preventing this infection in young children during outpatient care.
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In a 15-year pediatric time-series analysis, we showed a rise of invasive Group A streptococcal (iGAS) infections since October 2022, mainly involving pleural empyema, simultaneously to a respiratory virus outbreak. Physicians should be aware of this increased risk of pediatric iGAS infections, especially in settings with intense respiratory viruses' circulation.

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In this paper we describe a semantic approach for grouping medical terms into a hierarchy of concepts based on the UMLS meta-thesaurus. The context of this work is Medical Recap, a Web system that automatically extracts risk information from PubMed abstracts, and then aggregates this knowledge into dependence graphs or Bayesian networks.

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Dependence relations among disease and risk factors are a key ingredient in risk modeling and decision support models. Currently such information is either provided by experts (costly and time consuming) or extracted from data (if available). The published medical literature represents a promising source of such knowledge; however its manual processing is practically infeasible.

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Aim: The purpose of our study was to determine clinical, biological or endoscopic factors that predict surgery after a glucocortico steroid treatment failure in severe attacks of ulcerative colitis.

Methods: Sixty one patients were analyzed. A therapeutic response for glucocorticosteroid was defined as the absence of resort to surgery within the first 30 days after hospitalization.

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