Publications by authors named "Y L Boteon"

Article Synopsis
  • Short Bowel Syndrome (SBS) is a rare gastrointestinal disorder leading to intestinal failure (SBS-IF), and intestine transplantation (IT) is a potential treatment that can help patients return to normal activities.
  • This study analyzed the clinical characteristics and outcomes of SBS-IF patients who underwent IT in Brazil from 2011 to 2021, focusing on a small group of young males.
  • Key findings reveal that the main reasons for IT included surgical complications and liver disease related to total parenteral nutrition, highlighting the need for insights that could guide health policy and improve patient care.
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Article Synopsis
  • Scientists are studying how to tell if a donated liver is healthy enough to use for transplant by looking at special markers during a process called HOPE.
  • They collected samples from livers in 10 different centers across 7 countries and found that the levels of a marker called FMN can help predict if the liver will work well after being transplanted.
  • The study showed that FMN is better at predicting liver problems compared to older methods, making it a promising tool for doctors to decide which livers are suitable for transplant.
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Purpose: Acute-on-chronic liver failure (ACLF) is a leading cause of death in cirrhotic patients. This study aims to describe the outcomes of in-patients with ACLF at a liver transplantation (LT) center in Brazil.

Methods: Retrospective study analyzing patient data from 2017 to 2022.

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Article Synopsis
  • The 2023 Joint Annual Congress for liver transplantation was held in Rotterdam from May 3 to 6, marking the first time all speakers attended in person since the COVID-19 pandemic.
  • The event gathered 1,159 delegates from 54 countries, showcasing 542 of the 647 submitted abstracts, with a significant portion coming from just 10 countries, mainly in North America, Europe, and Asia.
  • Abstracts covered various topics including ischemia and reperfusion injury, machine perfusion, and artificial intelligence, while also evaluating scientific impact through publications resulting from prior presentations in the field.
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Normothermic machine perfusion (NMP) enables pretransplant assessment of high-risk donor livers. The VITTAL trial demonstrated that 71% of the currently discarded organs could be transplanted with 100% 90-day patient and graft survivals. Here, we report secondary end points and 5-year outcomes of this prospective, open-label, phase 2 adaptive single-arm study.

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