Publications by authors named "Y L Begrambekova"

Objective: To assess the prevalence of risk factors  of cardiovascular disease (CV RF) development and awareness of them among young people studing at University.

Material And Methods: Сross-sectional study study included 1182 young men and women studying at Lomonosov Moscow State University (age 18-44 years), with no history of chronic non-infectious diseases, who underwent a screening  in April-June 2022. All participants filled out the standard "Questionnaire for citizens under the age of 65 years to identify chronic non-communicable diseases, risk factors for their development, and the use of narcotic drugs and psychotropic substances without prescription", a specially designed questionnaire on socio-demographic characteristics and risk factors for CVD development, and a questionnaire on nighttime sleep status.

View Article and Find Full Text PDF

Aim      To evaluate the role of iron deficiency (ID) identified by various criteria, anemia, and the combination of ID and anemia in determining the severity of the clinical course of chronic heart failure (CHF) in a retrospective analysis of data from 498 patients who participated in the ID-CHF-RF Russian multicenter program.Material and methods  ID was diagnosed by the following three criteria established by the European Society of Cardiology (ESC) and the Russian Society of Cardiology (RSC): 1) ferritin concentration <100 μg/l or ferritin concentration 100-299 μg/l in combination with a decreased transferrin saturation (TS) <20%; 2) ID criteria that showed a high sensitivity and specificity when compared with bone marrow morphology (BMM): TS ≤19.8% or serum iron (SI) ≤13 μmol/l; and 3) a composite index including a ferritin concentration <100 μg/l in combination with TS <20% and SI ≤13 μmol/l.

View Article and Find Full Text PDF
Article Synopsis
  • The CHANCE study investigated the effects of a monitoring and education program for patients with chronic heart failure, comparing an intervention group (IG) receiving structured support to a control group (CG) receiving standard care.
  • Results showed that the IG had significantly lower mortality rates (8.3%) compared to the CG (13.0%), and a relative risk of 0.68 for death, indicating the program's effectiveness in saving lives.
  • Additionally, the IG exhibited better improvements in clinical condition, functional capabilities (as seen in the 6-minute walk test), and overall quality of life, with significant reductions in anxiety and depressive symptoms over 12 months.
View Article and Find Full Text PDF
Article Synopsis
  • The study compares clinical and lab data of chronic heart failure (CHF) patients with iron deficiency (ID) based on two different diagnostic criteria: AHA/ESC/RSC guidelines and a stricter definition involving low transferrin saturation (TSAT) and serum iron levels.
  • Among 498 patients analyzed, ID was identified in 83.1% using AHA/ESC/RSC criteria and 74.5% using the TSAT/serum iron criteria, with many patients meeting both sets of criteria.
  • Those diagnosed with ID based on the TSAT/serum iron criteria experienced more severe CHF symptoms, higher rates of anemia and diabetes, and showed significant differences in lab results and age compared to those diagnosed solely
View Article and Find Full Text PDF

Assessing the functional capacity and exercise tolerance is an important and widely used research tool in patients with heart failure. It is used not only in cardiac rehabilitation and physical therapy, but also for inclusion criteria and outcome measures in studies of drug interventions. This document outlines the scope, guidelines for the implementation and interpretation, and limitations of the methods for assessing the functional capacity and exercise tolerance in clinical trials in patients with heart failure.

View Article and Find Full Text PDF