Publications by authors named "Y Koshizuka"

Article Synopsis
  • - Familial adenomatous polyposis (FAP) is an inherited condition linked to mutations in the APC gene, leading to many colorectal polyps and a high risk of colorectal cancer, usually diagnosed through colonoscopy.
  • - Recent advancements like whole-genome array comparative genomic hybridization (a-CGH) have improved the detection of genetic imbalances associated with FAP, allowing for more precise patient assessment.
  • - In a study focusing on patients with complete APC gene deletions, researchers found varied genetic loss sizes and identified EPB41L4A as a candidate gene that may be linked to neurodevelopmental issues in some patients.
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Background: In patients with pancreaticobiliary maljunction complicated by congenital biliary dilatation, the pancreatic enzyme flows back into the bile, leading to bile duct carcinogenesis. Although the biliary tract resection and reconstruction is well documented to decrease the rate of malignancy, cancer occurrence has been reported in the residual intrahepatic or intrapancreatic bile duct, even after resection. We report a case of multiple biliary tract cancers in the liver complicated by congenital biliary dilatation, whose tumor lesions were resected en bloc without disconnecting the biliary tract by simultaneous pancreatoduodenectomy and living donor liver transplantation.

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Gastrointestinal stromal tumors surrounding the esophagogastric junction are often challenging to resect, with no consensus regarding the optimal surgical technique. Here in, we present a case of concurrent gastric cancer in the antrum and gastrointestinal stromal tumors adjacent to the esophagogastric junction. The patient underwent simultaneous distal gastrectomy and local resection assisted by a surgical robot, avoiding the need for total gastrectomy.

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Ammonia is an extremely important storage and transport medium for renewable energy, and technology is expected to produce it on demand and onsite using renewable energy. Applying a DC (direct current) to a solid catalyst layer with semiconducting properties makes ammonia synthesis highly efficient, even at low temperatures (approximately 400 K). In this process, oxide supports with semiconducting properties play important roles as metal supports and conduction fields for electrons and protons.

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Castleman disease (CD) is a rare lymphoproliferative disease. Hyaline-vascular type unicentric CD has a good prognosis if completely resected during surgery. However, follicular dendritic cell proliferative lesions have the potential for recurrence and metastasis.

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