Publications by authors named "Y Koide"
Utility values of responders and nonresponders are essential inputs in cost-effectiveness studies of radiation therapy for painful bone metastases but, to our knowledge, they have not been reported separately. We sought to determine the utility values of responders and nonresponders using data from a prospective observational study on bone metastases. The original prospective observational study was conducted at 26 centers in Japan.
View Article and Find Full Text PDFPurpose: A novel classification system has been proposed to stratify patients undergoing palliative radiation therapy based on their pain response and time to progression. This study used prospective observational data to quantify quality of life (QoL) changes associated with pain response and the classification system.
Methods And Materials: Between August 2021 and September 2022, 366 painful lesions with a numerical rating scale of 2 or more from the 261 eligible patients underwent palliative radiation therapy.
Article Synopsis
- - The study analyzed the impact of immunotherapy on 67 patients with unresectable stage IVB gastric cancer treated at Yarita Hospital, comparing outcomes from an early group (2016-2017) and a late group (2018-2022).
- - Nivolumab was administered to 30% of patients, with a median overall survival of 11 months, showing longer survival in the early group compared to the late group (13 vs. 8.5 months). Transition rates to third-line treatments also increased from 22% to 33% over the study period.
- - The findings suggest that the introduction of new therapies has improved treatment options for patients with advanced gastric cancer, indicating a trend towards better management
Article Synopsis
- This study aimed to evaluate the real-world impact of radiotherapy for bone metastases on patients' quality of life (QOL) using data from 26 centers in Japan.
- Out of 333 patients receiving treatment, 232 were included, and their QOL was assessed at enrollment and followed up at two and six months using standardized questionnaires.
- Results showed significant improvements in several QOL areas, especially pain and insomnia, indicating that radiotherapy can positively affect some aspects of patient well-being in practice.