Publications by authors named "Y Kil"
Article Synopsis
- Understanding plant metabolites across the plant kingdom is challenging due to their vast diversity.
- Researchers created the plantMASST reference database with data from 19,075 plant extracts, covering 246 botanical families, 1,469 genera, and 2,793 species.
- This database enhances research on plant molecules, supporting drug discovery, biosynthesis, taxonomy, and ecology related to herbivore interactions.*
Mesenchymal stem cell (MSC)-based therapies show great potential in treating various diseases. However, control of the fate of injected cells needs to be improved. In this work, we developed an efficient methodology for modulating chondrogenic differentiation of MSCs.
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- Twenty-one dihydropyranocoumarins and one furanocoumarin were isolated from the flowers of Peucedanum japonicum, including four new compounds.
- The structures and stereochemistry of the new compounds were determined using advanced techniques like nuclear magnetic resonance and mass spectroscopy.
- The isolated compounds were tested for their ability to inhibit aldo-keto reductase 1C1 in lung cancer cells, with compounds 10 and 12 showing notable inhibitory activity.
Article Synopsis
- Wheat is the second most cultivated food crop globally, known for its high carbohydrate content and nutritional benefits, but it also produces a significant amount of hull as a non-food by-product.
- Researchers studied hulls from gamma-irradiated mutant lines of cultivated wheat to extract functional components, using advanced mass spectrometry techniques to identify a total of 55 metabolites, including 21 compounds never seen before in wheat.
- They identified 10 metabolites as key markers with anti-inflammatory properties, suggesting that wheat hull is a promising source for beneficial tricin-lignan compounds.