Publications by authors named "Y Khafaga"

Background: Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children occurring most commonly in the head and neck region. The treatment involves using a multimodality approach including chemotherapy, surgery, and radiation therapy. Survival for patients with localized disease has improved markedly, but the treatment of advanced disease remains a challenge.

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Introduction: After high dose chemotherapy (HDC) and autologous stem cell transplantation (auto-SCT), in patients with relapsed/refractory diffuse large B cell lymphoma (DLBCL) and Hodgkin lymphoma (HL), involved field radiation therapy (RT) for consolidation and residual/progressive disease (PD) eradication is a common practice.

Materials And Methods: Retrospective single-institution cohort analysis to evaluate the impact of early RT after HDC auto-SCT.

Results: Between 1996 and October 2019, 153 patients (43 DLBCL, 110 HL) underwent RT after HDC auto-SCT.

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Background: In 2015, multiple myeloma (MM) represented 1% of all cancers and about 5% of hematologic malignancies in Saudi cancer registry. We conducted this large study because only small pilot studies have examined MM outcomes after autologous stem-cell transplantation (ASCT). The standard therapy for eligible patients is induction chemotherapy followed by ASCT.

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Article Synopsis
  • Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a rare type of Hodgkin lymphoma, and this study focuses on the effectiveness of FDG-PET scans in staging and monitoring treatment response in patients.
  • The research analyzed data from 68 patients who had undergone both CT and FDG-PET scans before and after treatment, finding that FDG-PET and CT scans agreed in 80% of cases for staging.
  • The results indicated that FDG-PET is more reliable than CT for treatment response evaluation, showing better specificity despite some discrepancies in disease status assessment.
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Background: Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is an uncommon variant of Hodgkin lymphoma. There is limited data on treatment, management of refractory and relapsed disease, and long-term outcome. Many registries or country-wide data reports are unable to provide detailed primary and subsequent management.

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