Adverse reactions among patients being treated for MDR-TB in Tomsk, Russia.

Background And Significance: Treatment of multidrug-resistant tuberculosis (MDR-TB) is challenging because of the toxicity of second-line medications. Little is known about whether adverse events impact treatment outcome.

Methods: We conducted a retrospective case series of 244 MDR-TB patients enrolled in Tomsk between 10 September 2000 and 10 September 2002.

Treatment outcomes in an integrated civilian and prison MDR-TB treatment program in Russia.

Setting: Multidrug-resistant tuberculosis (MDR-TB) is a major problem in countries of the former Soviet Union in both the civilian and prison sectors.

Objective: To evaluate outcomes of the MDR-TB treatment program (DOTS-Plus) in Tomsk, Russia.

Design: Retrospective case series of all patients enrolled in this program between 10 September 2000 and 10 September 2002.