Publications by authors named "Y Kamijo"
Background: In cell-free and concentrated ascites reinfusion therapy (CART), filtration membrane obstruction during the ascites processing step is an important clinical problem. A novel membrane designed polyether sulfone filter (n-PES) was developed to reduce filter membrane obstruction. However, no clinical studies have compared the performance of n-PES filters with that of conventional filters.
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- Systemic capillary leak syndrome (SCLS) is a rare and dangerous condition, highlighted by a case involving a man in his 60s who presented with severe fatigue, low urine output, and mobility issues.
- He experienced prerenal acute kidney injury (AKI) characterized by specific lab findings and required substantial intravenous fluid treatment to regain kidney function, but he suffered multiple AKI episodes during his hospital stay.
- Ultimately, he was diagnosed with idiopathic SCLS and treated with intravenous immunoglobulin; this case stresses the importance of recognizing signs of SCLS in patients with recurrent AKI to prevent complications.
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- A 20-year-old woman was hospitalized after consuming high doses of caffeine (18g) and mexiletine (3500mg), leading to severe hypotension, tachycardia, hypokalemia, and lactic acidosis.
- She underwent multiple medical interventions, including mechanical ventilation, noradrenaline infusion, and hemodialysis (HD), as her condition worsened to pulseless ventricular tachycardia requiring VA-ECMO support.
- The case highlighted that mexiletine may hinder caffeine clearance, complicating treatment; however, after HD, her drug levels decreased significantly, allowing successful recovery and weaning from life support within a few days.
A 25-year-old Japanese man developed visual disturbance with eye pain and was diagnosed with optic neuritis associated with anti-myelin oligodendrocyte glycoprotein antibodies. His symptoms improved temporarily after steroid therapy but chronically relapsed many times after tapering the steroid dose. He became highly steroid-dependent and was referred to our department for reconsideration of the treatment strategy.
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