Publications by authors named "Y K Kwok"

Background: Meta-analyses (MAs) provide up-to-date, quantified evidence on treatment effects, which may be useful for clinical and policy decision-making. However, the quality of MAs varies, and methodological flaws can limit their reliability.

Aims: This review evaluated the methodological quality of MAs on sleep disorder treatments.

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Article Synopsis
  • A series of organic dyes based on 9,9'-dihexylfluorene with unique electron-donating groups were created to improve photocatalytic hydrogen evolution (PHE) performance.
  • These dyes achieved impressive results, including a turnover number (TON) of 17,400 and hydrogen production of 1,090 μmol over 126 hours under visible light.
  • The research highlights that the dianchoring design significantly boosts PHE efficiency and durability compared to traditional organic dyes, marking it as a leading system for hydrogen production.
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Purpose: Increasing concern that brainstem toxicity incidence after proton radiation therapy might be higher than with photons led to a 2014 University of Florida (UF) landmark paper identifying its risk factors and proposing more conservative dose constraints. We evaluated how practice patterns changed among the Pediatric Proton/Photon Consortium Registry (PPCR).

Material And Methods: This prospective multicenter cohort study gathered data from patients under the age of 22 years enrolled on the PPCR, treated between 2002 and 2019 for primary posterior fossa brain tumors.

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  • The study assessed the effectiveness of cell-free DNA (cfDNA) testing for detecting chromosomal abnormalities in multiple pregnancies, specifically twins, triplets, and cases of vanishing twins.
  • Data from 292 pregnancies showed that cfDNA testing was particularly effective for trisomy 21, with a 100% confirmation rate and a 0% false positive rate in twin pregnancies.
  • The research concluded that while cfDNA testing is reliable for assessing trisomy 21 in twin pregnancies, its ability to detect other chromosomal abnormalities is limited due to the small number of cases.
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