The basic helix-loop-helix (bHLH) family members are involved in plant growth and development, physiological metabolism, and various stress response processes. is a major turpentine-producing and wood-producing tree in seasonally dry areas of southern China. Its economic and ecological values are well known.
View Article and Find Full Text PDFDuring the production of medical thin-walled tubes, a thin coating layer is required. This requirement reduces the cross-sectional clearance area of the straight section flow channel formed by the mandrel and the die, leading to excessive pressure of the polymer melt at the shaping section, elevated die pressure, and backflow of the material melt, all of which directly impact the quality of the coating layer. To address these issues, this study conducted a non-isothermal numerical simulation of coating models both with and without a shaping section.
View Article and Find Full Text PDFTetrodotoxin (TTX), a potent Site-1 sodium channel blocker (S1SCB), offers highly effective local anesthetic properties with minimal addiction potential. To fully leverage TTX's capabilities as a local anesthetic, it is crucial to develop a drug delivery system that balances its systemic toxicity with its therapeutic efficacy. Recent studies have shown that peptide mixtures, derived from fragments of Site-1 sodium channel proteins and enhanced with hydrophobic tails (designated MP1 and MP2), can self-assemble into nanostructures that exhibit remarkable sustained-release capabilities for TTX.
View Article and Find Full Text PDFPolygonatum cyrtonema Hua (Duohua Huangjing, Asparagaceae in angiosperms) is a traditional medicinal and edible plant in China. Its rhizomes can potentially enhance immunity, reduce tumor growth and the effects of aging, improve memory, and even reduce blood sugar levels (Zhao et al. 2020).
View Article and Find Full Text PDFJ Cardiothorac Surg
January 2025
Objective: In this study, we aimed to screen the risk factors for delayed extubation after surgery for Ebstein's anomaly (EA), determine the diagnostic cut-off values, and develop a prediction equation to accurately encourage rapid recovery after surgery.
Methods: The perioperative data of 76 pediatric patients undergoing EA surgery in the Surgical Department of the Pediatric Heart Center of Anzhen Hospital from September 2013 to September 2021 were retrospectively analyzed.
Results: Among these cases, 37 (48.