Publications by authors named "Y Janssens"
In a Phase 2a, double-blind, placebo-controlled study including healthy participants aged 18-55 years, OVX836, a nucleoprotein (NP)-based candidate vaccine, previously showed a good safety profile, a robust immune response (both humoral and cellular) and a preliminary signal of protection (VE = 84%) against PCR-confirmed symptomatic influenza after a single intramuscular dose of 180 µg, 300 µg or 480 µg. : Using the same methodology, we confirmed the good safety and strong immunogenicity of OVX836 at the same doses in older adults (≥65 years), a key target population for influenza vaccination. : Significant humoral (anti-NP IgG) and cellular (interferon gamma (IFNγ) spot-forming cells per million peripheral blood mononuclear cells and specific CD4 IFNγ T-cells) immune responses were observed at the three dose levels, without clear dose-response relationship.
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- The study aimed to determine if the inclination of lower anterior teeth can be effectively managed after lower premolar extractions in patients undergoing Class III camouflage treatment with customized lingual appliances.
- It involved a sample of 25 patients, with assessments made before and after treatment to measure changes in skeletal and dental alignment using lateral head films and statistical tests.
- Findings indicated that despite the extractions, the lower incisor inclination improved significantly, confirming that lower premolar extractions can effectively aid in correcting Class III malocclusions without causing further retroclination of the incisors.
Objectives: The aim of this investigation was to evaluate whether Class II malocclusion in adult patients can be successfully corrected using a completely customized lingual appliance (CCLA) in combination with Class II elastics.
Methods: In order to detect differences in the final treatment outcome, two groups were matched for age and gender. Treatment results of 40 adult orthodontic patients with a Class I malocclusion (Group 1) were compared to 40 adults with a Class II malocclusion (Group 2).
Article Synopsis
- - This investigation aimed to see if adult patients with Class II malocclusion could be treated effectively using maxillary total arch distalization with mini-screws and customized lingual appliances.
- - The study involved comparing treatment outcomes between two groups: 40 patients with Class I malocclusion and 40 with moderate to severe Class II malocclusion, using a grading system for orthodontic models.
- - Results showed significant improvement in both groups, with Class II patients achieving nearly all planned corrections, and both groups meeting the American Board of Orthodontics standards after treatment, indicating the method's effectiveness.
Objectives: X-linked hypophosphatemia (XLH) is a rare genetic disease that disturbs bone and teeth mineralization. It also affects craniofacial growth and patients with XLH often require orthodontic treatment. The aim of this study was to describe changes in the dental health of XLH children during orthodontic treatment compared with those in matched controls undergoing similar orthodontic procedures.
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