Assessment of factors associated with antipsychotic-induced weight gain: A nationwide cohort study.

Background: The incidence of antipsychotic-induced weight gain (AIWG) is difficult to predict in real-world practice because various factors influence it. This study aimed to explore background and medication-related factors associated with weight gain in patients newly prescribed with antipsychotic medication.

Methods: This nationwide, multicenter, prospective cohort study was conducted in Japan.

A 25-year clonal resurrection in adult T-cell leukemia-lymphoma relapse.

Here, we report a rare case of relapsed adult T-cell leukemia-lymphoma (ATL) with evidence of clonal relapse 26 years after initial diagnosis. The patient had been diagnosed with an aggressive form of lymphoma-type ATL 26 years prior and did not receive further ATL treatment for approximately 26 years after achieving complete remission. We used nested PCR to identify the amplification of ATL clone-specific accumulation sites in DNA from hematoxylin and eosin-stained specimens from the patient.

The role of anchoring information in judgments of learning.

This study examined informative and uninformative anchoring effects on judgments of learning (JOLs), focusing on two hypotheses: the optimistic/pessimistic and differential-scaling hypotheses. The optimistic/pessimistic hypothesis states that anchoring information changes subjective confidence in memory, whereas the differential-scaling hypothesis states that anchoring information elicits a scaling bias in the conversion process of subjective internal confidence into scale JOLs (i.e.

Clinical Practice Guidelines for the Management of Congenital Syphilis in Japan, 2023: Executive Summary.

Congenital syphilis (CS) is a mother-to-child infection caused by the bacterium Treponema pallidum, transmitted through the placenta. In Japan, the number of syphilis cases has recently increased, accompanied by an increase in CS cases. Thus, automated methods for serum antibodies with serial values, without a 2× dilution sequence, have been widely used.

Identification of a Founder GLDN Variant Associated With "Lethal" Arthrogryposis in Nunavik Inuit: Implications for Obstetrical and Long-Term Survivors' Management.

Biallelic variants in GLDN have recently been associated with lethal congenital contracture syndrome 11 (LCCS11), a form of fetal akinesia deformation sequence (FADS) with high neonatal mortality. In this report, we describe five individuals from two Canadian Inuit families originating from different communities in Nunavik all affected with FADS and harboring a rare homozygous missense variant, [NM_181789.4:c.