Publications by authors named "Y Ishiuji"

Article Synopsis
  • Prurigo chronica multiformis is a specific type of skin condition primarily recognized in Japan, especially among elderly patients, characterized by extremely itchy, swollen patches on the skin.
  • The lesions evolve from small, itchy bumps to more solid nodules that might group together, often appearing on areas like the lower abdomen and lower back.
  • There is a need for more research on its incidence, variations based on geography, and how it relates to other skin diseases, and dermatologists should be informed about its unique clinical features.
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Article Synopsis
  • Atopic dermatitis (AD) is a chronic skin disease characterized by intense itching, and new treatments like dupilumab have been developed but predicting the right treatment for each patient is challenging.
  • A study involving 110 AD patients aimed to identify factors and biomarkers that could indicate how well patients might respond to dupilumab, using various scales for assessment.
  • Findings showed that higher baseline serum LDH levels and certain comorbidities, like food allergies, were linked to poorer treatment outcomes, suggesting these could help guide treatment decisions for AD patients.
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Itch is a protective/defensive function with divalent motivational drives. Itch itself elicits an unpleasant experience, which triggers the urge to scratch, relieving the itchiness. Still, it can also result in dissatisfaction when the scratch is too intense and painful or unsatisfactory due to insufficient scratch effect.

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Background: Itch is the most troublesome symptom of atopic dermatitis, and it is important to assess it appropriately for optimal treatment. We discussed issues regarding itch and the most appropriate methods of assessment at the Atopic Itch Consensus Meeting (AICOM), attended by physicians and researchers with expertise in itch treatment and research.

Methods: The AICOM participants prepared a draft consensus statement that addressed the most appropriate itch assessment methods for age groups <2 years, 2-6 years, 7-14 years, and ≥15 years.

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