Improved emulsifying and foaming properties of ovalbumin and antioxidant activity of (-)-gallocatechin gallate: Effects of ultrasound-assisted glycation based on natural deep eutectic solvents and noncovalent binding.

In this study, ultrasound-assisted glycated ovalbumin (G-UOVA) based on natural deep eutectic solvents (NADES) was prepared using response surface optimization. The binding affinity of (-)-gallocatechin gallate (GCG) to native OVA (NOVA), ultrasound treated OVA (UOVA), glycated OVA (GOVA), and G-UOVA followed G-UOVA > GOVA > UOVA > NOVA. The effects of various modifications and GCG binding on the secondary structure, particle size, and thermal stability of NOVA were investigated.

A Prebiotic Route to Lactate from Acetaldehyde, Cyanide and Carbon Dioxide.

The atmospheric concentration of carbon dioxide (CO2) has fluctuated throughout Earth's history. However, the role of CO2 in prebiotic chemistry has predominantly been limitedly postulated as a C1 precursor, which can be reduced to carbon monoxide or methane mimicking the Wood-Ljungdahl pathway. Herein we present neglected roles of CO2 as an active promoter in accessing biologically important C3-builidng blocks such as lactate, via redox-economic reaction cycles from cyanide (C1) and acetaldehyde (C2).

Heterogeneity and permeability estimation of pore-throat structure at different scales in deep tight sandstone reservoirs: A case study of Paleogene Hetaoyuan Formation in Anpeng area, Nanxiang Basin, China.

Clarifying the pore-throat size and pore size distribution of tight sandstone reservoirs, quantitatively characterizing the heterogeneity of pore-throat structures, is crucial for evaluating reservoir effectiveness and predicting productivity. Through a series of rock physics experiments including gas measurement of porosity and permeability, casting thin sections, scanning electron microscopy, and high-pressure mercury injection, the quality of reservoir properties and microscopic pore-throat structure characteristics were systematically studied. Combined with fractal geometry theory, the effects of different pore throat types, geometric shapes and scale sizes on the fractal characteristics and heterogeneity of sandstone pore throat structure are clarified.

Prevalence of Disability Among Older Adults in Prison.

Importance: The number of older adults in long-term correctional facilities (prisons) has increased rapidly in recent years. The cognitive and functional status of this population is not well understood due to limitations in the availability of longitudinal data.

Objective: To comparatively examine the prevalence and disability status of the population of adults 55 years and older in prisons and adults living in community settings for a 14-year period (2008-2022).

Paroxetine promotes longevity via ser-7-dop-4-IIS axis in Caenorhabditis elegans.

Paroxetine, a selective serotonin reuptake inhibitor, is widely used in the clinical treatment of depression. While several antidepressants show promise as geroprotectors, the role of paroxetine in aging remains unclear. In this study, we evaluated the lifespan extension effect of paroxetine in Caenorhabditis elegans (C.