Publications by authors named "Y Iizumi"

Article Synopsis
  • - The study investigated the safety of proton beam therapy (PBT) for localized prostate cancer using a shortened treatment plan of 70 Gy in 28 fractions, which had been previously well-researched for conventional radiotherapy.
  • - A total of 102 men participated, with risk classifications ranging from low to high, and toxicity effects were monitored throughout the study using standardized criteria.
  • - The results showed a low occurrence of serious side effects after 5 years, with only 1% experiencing grade 2 gastrointestinal issues and 4% facing grade 2 genitourinary issues, confirming the safety of the hypofractionated PBT approach.
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Ecotoxicity data on cellulose nanofibers (CNFs) are limited despite their wide potential applications prospects, such as structural and packaging materials, filters, coatings, foods, and cosmetics. In this study, toxicity tests of 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-oxidized CNFs (TEMPO-CNFs), which are one of the major CNF products commercially available in Japan, on the green alga Raphidocelis subcapitata were conducted. As nanomaterials are considered difficult-to-test substances, the Organisation for Economic Co-operation and Development has released a guidance document that provides considerations regarding ecotoxicity tests of nanomaterials.

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Neuroblastomas are the most common extracranial solid tumors in children and have a unique feature of neuronal differentiation. Peroxisome proliferator-activated receptor (PPAR)-γ is reported to have neuroprotective effects in addition to having antitumor effects in various cancers. Thus, we aimed to clarify the role of PPAR-γ agonist and antagonist in malignant neuroblastomas, which also possess neuronal features.

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Objectives: This study aimed to investigate the effects of interferential current electrical stimulation (IFCS) on masticatory and swallowing function.

Materials And Methods: Twenty healthy young adults were enrolled. The measurement items were spontaneous swallowing frequency (SSF), voluntary swallowing frequency (VSF), saliva secretion volume (SSV), glucose elution volume (GEV), and velocity of chew (VOC).

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Nanocellulose is a remarkable biomaterial. It is a plastic alternative with significance from the viewpoint of carbon offset and neutrality. To efficiently develop nanocellulose-based functional materials, it is imperative to evaluate their dispersion states.

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