Comparison of ex vivo lesion formation for two adjacent radiofrequency applications with very high-power short-duration in various inter-lesion times.

Background/objectives: Very high-power and short-duration (vHPSD) ablation with QDOT MICRO™ facilitates speedy and safe ablation for pulmonary vein isolation. A brief time interval between ablating two neighboring sites with vHPSD may potentially influence the size and geometry of the lesions. This study evaluates lesion formation when delivering adjacent applications using vHPSD at various inter-lesion times (ILTs).

Anxiety and Depression in Japanese Patients with Genitourinary Syndrome of Menopause.

Introduction And Hypothesis: Women with genitourinary syndrome of menopause (GSM) may have anxiety and depression; however, this is unclear.

Methods: A total of 646 postmenopausal women undergoing treatment for menopausal symptoms were enrolled in this retrospective cross-sectional study. Questionnaire responses were recorded at the first visit, and participants were divided into GSM (≥1 moderate or severe GSM symptom) or no-GSM (without any moderate/severe symptoms) groups.

Mental health and quality of life in patients with premenstrual exacerbation: a cross-sectional study in Japan.

Background: In the classification of premenstrual disorders (PMDs), premenstrual exacerbation (PME) is listed as one of the variants of PMDs, along with core PMD. However, the incidence of PME and its impact on mental health and quality of life have not been investigated. Therefore, we investigated the proportion of PME among women seeking treatment for premenstrual symptoms in Japan and compared the levels of anxiety, depression and quality of life between women with PME and those with core PMD.