Structure of Hydrothermally Stable Acid Sites and their Catalytic Role in P-Modified ZSM-5 Zeolite Revealed by Solid-State NMR Spectroscopy.

The ZSM-5 zeolite is the key active component in high-severity fluid catalytic cracking (FCC) catalysts and is routinely activated by phosphorus compounds in industrial production. To date, however, the detailed structure and function of the introduced phosphorus still remain ambiguous, which hampers the rational design of highly efficient catalysts. In this work, using advanced solid-state NMR techniques, we have quantitatively identified a total of seven types of P-containing complexes in P-modified ZSM-5 zeolite and clearly revealed their structure, location, and catalytic role.

Biomimetic Extracellular Vesicles Containing Biominerals for Targeted Osteoporosis Therapy.

Osteoporosis (OP) is a systemic skeletal disorder characterized by decreased bone mineral density and a heightened risk of fractures. Therapies for OP have primarily focused on balancing bone formation and bone resorption, but enhancing the remineralization of osteoporotic bone is also a key strategy for effective repair. Recent insights into biomineralization mechanisms have highlighted the essential role of mineral-containing extracellular vesicles (EVs) secreted by osteoblasts in promoting bone marrow mesenchymal stromal/stem cell (BMSC) differentiation and initiating matrix mineralization.

Spatial suitability evaluation and layout optimization of emergency shelter: A case study in Tianhe District of Guangzhou City.

Emergency shelters are multifunctional spaces that provide safe refuge, essential life protection, and rescue command for residents in case of urban disaster. These shelters constitute crucial components of urban public safety. This study, with Tianhe District in Guangzhou City as a case study, used data from emergency evacuation sites and other socio-economic sources to construct an evaluation system for spatial suitability evaluation and layout optimization of emergency shelters.

Evaluating cardiac performance in beagle dogs: Transesophageal echocardiography and myocardial work assessment.

Objectives: This study aimed to establish standard transesophageal echocardiographic (TEE) measurements of left ventricular (LV) morphology, function, and myocardial work parameters in healthy Beagle dogs using pressure-strain loops (PSL). Additionally, it sought to standardize optimal TEE imaging techniques and explore the potiential application of myocardial work analyis in veterinary medicine.

Methods: Thirty-seven healthy male Beagle dogs were anesthetized, intubated, and mechanically ventilated for TEE examinations.

Intestinal epithelial cell NCoR deficiency ameliorates obesity and metabolic syndrome.

Nuclear receptor corepressor (NCoR1) interacts with various nuclear receptors and regulates the anabolism and catabolism of lipids. An imbalance in lipid/energy homeostasis is also an important factor in obesity and metabolic syndrome development. In this study, we found that the deletion of NCoR1 in intestinal epithelial cells (IECs) mainly activated the nuclear receptor PPAR and attenuated metabolic syndrome by stimulating thermogenesis.