Zh Vopr Neirokhir Im N N Burdenko
December 2024
Unlabelled: The development of new drugs in nuclear medicine for diagnosis or treatment (chemotherapy) of brain tumors, in particular gliomas, is inextricably linked with the use of tumor models in animals (usually rats).
Objective: To compare the widely used glioma cell model C6 and the new experimental tissue model of glioblastoma 101.8.
Bacteria of the genus, including the subgroup, play an important role in the environmental microbial communities. Psychrotolerant isolates of can produce thermostable proteases and lipases. When contaminating refrigerated raw milk, these bacteria spoil it by producing enzymes resistant to pasteurization.
View Article and Find Full Text PDFBacteria of the genus are significant challenge for medicine, as many species are resistant to multiple antibiotics and some are even to all of the antibiotics we use. One of the approaches to developing new therapeutics to treat staphylococcal infections is the use of bacteriophages specific to these bacteria or the lytic enzymes of such bacteriophages, which are capable of hydrolyzing the cell walls of these bacteria. In this study, a new bacteriophage vB_SepP_134 (St 134) specific to was described.
View Article and Find Full Text PDFwas discovered as a soil bacterium associated with the rhizosphere. Later, was found to be a multidrug-resistant hospital-associated pathogen. Lytic bacteriophages are prospective antimicrobials; therefore, there is a need for the isolation and characterization of new phages.
View Article and Find Full Text PDFMultidrug-resistant Gram-positive bacteria, including bacteria from the genus , are currently a challenge for medicine. Therefore, the development of new antimicrobials is required. Promising candidates for new antistaphylococcal drugs are phage endolysins, including endolysins from thermophilic phages against other Gram-positive bacteria.
View Article and Find Full Text PDF