Platinum resistance and sensitivity in recurrent/metastatic head and neck squamous cell carcinoma.

Objective: For patients with recurrent/metastatic head and neck squamous cell carcinoma (R/MHNSCC), platinum-free interval (PFI)-based differences in the effectiveness of rechallenge with platinum-based chemotherapy (PBCT) remain unknown. We aimed to evaluate the difference in platinum sensitivity based on PFI in R/MHNSCC.

Methods: We retrospectively examined 80 patients with R/MHNSCC who underwent PBCT between 2001 and 2020.

Pathological Level VI Lymph Node Metastasis in Clinical N3b Pyriform Sinus Squamous Cell Carcinoma.

Objective: The frequency of metastasis to level VI lymph nodes in advanced pyriform sinus squamous cell carcinoma (PSSCC) is unknown. We intended to analyze the clinical features and pathological presence or absence of level VI lymph node metastasis in patients with PSSCC.

Methods: The data of 270 patients with previously untreated hypopharyngeal squamous cell carcinoma from 2006 to 2016 were obtained.

Cardiac metastasis in a living patient with oral cancer.

Cardiac metastasis from head and neck cancers are very rare. Metastases to heart are mostly diagnosed at autopsy, and seldom found while patients are alive. Patients with cardiac metastasis do not present with specific symptoms in the early stages, and diagnosis is often delayed until the disease has advanced significantly.

Multiple Breath-hold Volumetric Modulated Arc Therapy Under Fluoroscopic Image Guidance with an Implanted Fiducial Marker: An Advanced Technique.

An advanced technique for multiple breath-hold volumetric modulated arc therapy (VMAT) has been proposed under fluoroscopic image guidance with a fiducial marker implanted close to a tumor. The marker coordinates on a digitally reconstructed radiography image at a gantry start angle, under a planned breath-hold condition, were transferred to the fluoroscopic image window. Then, a reference lateral line passing through the planned breath-hold marker position was drawn on the fluoroscopic image.

Role of 3D-TOF magnetic resonance angiography for intracranial meningioma.

Three-dimensional (3D) time of flight (TOF) magnetic resonance angiography (MRA) was performed in 13 patients with intracranial meningioma. 3D-TOF unenhanced MRA depicted arterial displacement by tumour, and poorly demonstrated the sinuses, veins and tumour mass. The direct visualization of the venous abnormalities on 3D-TOF MRA was improved by the administration of contrast material.