Publications by authors named "Y Hiyoshi"

Objectives: Peritoneal metastasis indicates a poor prognosis in patients with colorectal cancer (CRC). Studies have shown improved prognosis in patients after removal of peritoneal dissemination, and this surgery is recommended if not excessively invasive. The aim of this study was to examine clinical outcomes and prognostic factors for R0 resected CRC with synchronous peritoneal metastasis.

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Article Synopsis
  • Dyskeratosis congenita (DKC) is a genetic disease characterized by skin pigmentation issues, nail problems, and leukoplakia, with around 8-10% of patients developing cancers, including colorectal cancer.
  • A case study involved a 25-year-old man with DKC who was diagnosed with locally advanced rectal cancer, receiving total neoadjuvant therapy (chemotherapy followed by chemoradiation), which initially reduced the tumor.
  • Despite a near-complete response, the patient experienced tumor regrowth five months later and underwent a total pelvic exenteration surgery, after which he has remained cancer-free for one year.
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Purpose: Lateral pelvic lymph node (LPLN) metastasis of rectal neuroendocrine tumors (NETs) is rare, with unknown oncological features. We investigated the oncological impact of LPLN metastasis in patients with rectal NETs.

Methods: This study included 214 patients with rectal NETs who underwent curative surgery.

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Background/aim: Although chemotherapy for colorectal cancer has advanced remarkably, long-term chemotherapy can lead to a variety of infections. However, if chemotherapy must be discontinued to control infection, there is a risk of progression of colorectal cancer. Intracranial subdural empyema is a life-threatening intracranial infection.

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Background: Cytoreductive surgery and chemotherapy reportedly improve the prognosis of patients with metachronous peritoneal metastases. However, the types of peritoneal metastases indicated for cytoreductive surgery remains unclear. Therefore, we aimed to clarify the category of cases for which cytoreductive surgery would be effective and report the prognosis associated with cytoreductive surgery for metachronous peritoneal metastases.

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