Publications by authors named "Y Hisa"
Objectives: Spasmodic dysphonia (SD) is a rare disease and its epidemiological status is unclear. This review aimed to explore the current prevalence and clinical features of SD in Japan.
Methods: We reviewed Japanese surveys of SD and compared them to surveys reported from other countries.
Dia1, which belongs to the diaphanous-related formin family, influences a variety of cellular processes through straight actin elongation activity. Recently, novel DIA1 mutants such as p.R1213X (p.
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- - The oropharynx is traditionally examined using light sources and a tongue depressor, but it's hard to capture clear images of the tissue during this process.
- - Current methods for examining the pharynx are lacking in advancements, making it challenging to obtain consistent and objective observations.
- - This study aims to create a new type of oropharyngeal endoscope to improve the examination and visualization of the oropharynx.
Previous studies have convincingly argued that reactive oxygen species (ROS) contribute to the development of several major types of sensorineural hearing loss, such as noise-induced hearing loss (NIHL), drug-induced hearing loss, and age-related hearing loss. However, the underlying molecular mechanisms induced by ROS in these pathologies remain unclear. To resolve this issue, we established an in vivo model of ROS overproduction by generating a transgenic (TG) mouse line expressing the human NADPH oxidase 4 (NOX4, NOX4-TG mice), which is a constitutively active ROS-producing enzyme that does not require stimulation or an activator.
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