Salivary gland secretory carcinoma with an ETV6::RET fusion: A case report.

The present study reports the case of a 25-year-old male patient with salivary gland secretory carcinoma (SC) with the ETV6::RET gene fusion. The patient presented with a left parotid mass and was treated using a superficial parotidectomy. Histological analysis of the tumor demonstrated a combination of cystic, follicular and trabecular patterns in cells, with eosinophilic secretions and a vacuolated cytoplasm.

Deprotonation at Ring B Is an Intrinsic Property of the Bilin Chromophore in Cyanobacteriochrome RcaE.

Cyanobacteriochromes (CBCRs) are phytochrome-related photosensors that utilize a linear tetrapyrrole (bilin) as a chromophore. Cyanobacteriochrome RcaE belongs to the green/red-type subfamily that photoconverts between green-absorbing (Pg) and red-absorbing (Pr) states. This subfamily shows a protochromic photocycle, leveraging a protonation state change at the B ring pyrrole nitrogen (N) to induce a large absorption shift.

Virtual Monochromatic Imaging of Half-Iodine-Load, Contrast-Enhanced Computed Tomography with Deep Learning Image Reconstruction in Patients with Renal Insufficiency: A Clinical Pilot Study.

Background: We retrospectively examined image quality (IQ) of thin-slice virtual monochromatic imaging (VMI) of half-iodine-load, abdominopelvic, contrast-enhanced CT (CECT) by dual-energy CT (DECT) with deep learning image reconstruction (DLIR).

Methods: In 28 oncology patients with moderate-to-severe renal impairment undergoing half-iodine-load (300 mgI/kg) CECT by DECT during the nephrographic phase, we reconstructed VMI at 40-70 keV with a slice thickness of 0.625 mm using filtered back-projection (FBP), hybrid iterative reconstruction (HIR), and DLIR; measured contrast-noise ratio (CNR) of the liver, spleen, aorta, portal vein, and prostate/uterus; and determined the optimal keV to achieve the maximal CNR.

Temperature-stable high-power properties of (K,Na)NbO-based piezoelectric ceramics.

Piezoelectric ceramics tailored for high-power resonance applications are investigated, utilizing a composite structure comprising the ferroelectric phase (K,Na)NbO as a matrix integrated with the alkali titanoniobate dielectric phase KTiNbO. Achieving a mechanical quality factor of 750, comparable to lead-based counterparts, highlights their suitability for demanding applications. Crucially, these ceramics exhibit exceptional temperature stability of electromechanical properties, a critical attribute for real-world applications subject to temperature variations.

Preliminary Data on the Senolytic Effects of Ledeb. Extract Containing Agrimols for Immunosenescence in Middle-Aged Humans: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Comparison Study.

Objectives: To assess the effects of agrimol-containing Ledeb. extract (APE) for senescent immune cell removal in middle-aged Japanese adults with immunosenescence.

Design And Setting: A randomized, double-blind, placebo-controlled, parallel-group study was conducted in Japan between June 2023 and April 2024.