Identification of CTL epitopes in hepatitis C virus by a genome-wide computational scanning and a rational design of peptide vaccine.

Developing a peptide-based vaccine for the highly variable hepatitis C virus (HCV) remains a challenging task. Variant viruses not only escape antigen presentation but also persist in a patient as quasi-species. Such variants are often antagonistic to the responding T cell repertoire.

[Studies of antigens related to metabolic and growth inhibitions of Staphylococcus aureus L-form].

Metabolic and growth inhibiting activities in immunoglobulin (of anti-S. aureus L-form serum and anti-S. aureus coccal form serum) could be absorbed by cell membranes of S.