Publications by authors named "Y Higashiuesato"
Article Synopsis
- Colchicine has gained attention as an FDA-approved anti-inflammatory for cardiovascular diseases, though its low dose of 0.5 mg can cause side effects.
- The drug quickly leaves the bloodstream and enters leukocytes, which helps produce its anti-inflammatory effects.
- This study explores how colchicine behaves in plasma and leukocytes after taking 0.5 mg and 0.25 mg doses, finding that it remains in leukocytes even at lower dosages, potentially reducing side effects.
Background: Cortical gray matter (GM) and white matter (WM) deterioration are signals of neurodegeneration and increased dementia risk; however, their specific etiologies in dementia-free aging is unclear.
Objective: The objective of this study was to examine potentially modifiable risk factors of GM and WM degeneration in a well-characterized cohort of dementia-free elderly.
Methods: 96 Okinawan elderly participants (age 83.
Background: Epidemiological studies have found frequent consumption of fatty fish is protective against cognitive decline. However, the association between circulating omega-3 polyunsaturated fatty acid (PUFA) levels and cognitive functions among the oldest old is not well known.
Objective: To examine the association between serum PUFA levels and cognitive function among community-dwelling, non-demented elderly aged over 80 years old.
A 61-year-old man who was being treated with hemodialysis (HD) for end-stage renal disease presented with symptoms of severe congestive heart failure (CHF). Removing excess intravascular fluid during HD was difficult due to the patient's chronic hypotension induced by severe left ventricular (LV) dysfunction. The application of adaptive servo-ventilation (ASV) increased the patient's cardiac output and blood pressure during HD, thus resulting in the effective removal of excess intravascular fluid.
View Article and Find Full Text PDFWe are making efforts to reduce the number of venipuncture tubes for blood-based testing. On the reconstruction of hematology system in 2011, we planned the system to include hemoglobin A1c (HbA1c) assay and to replace the assay instrument for erythrocyte sedimentation rate (ESR) to use EDTA-2K based whole blood. Accordingly, the revised system required a single test tube for hematological testing, resulting in reduction of blood volume collected.
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