Publications by authors named "Y Heper"
An evaluation of a Stenotrophomonas maltophilia outbreak due to commercial arterial blood gas collection kit.
Antimicrob Resist Infect Control
May 2024
Background: Stenotrophomonas maltophilia is a gram-negative bacterium that can cause hospital infections and outbreaks within hospitals. This study aimed to evaluate an outbreak of Stenotrophomonas maltophilia, caused by ready-to-use commercial syringes containing liquid lithium and heparin for arterial blood gas collection in a university hospital.
Methods: Upon detecting an increase in Stenotrophomonas maltophilia growth in blood cultures between 15.
Surveillance of carbapenem-resistant and in perianal swab samples.
Infect Control Hosp Epidemiol
April 2024
Our study aimed to detect carbapenem-resistant (CRKP) and/or carbapenem-resistant in perianal swab samples, exploring their link to bloodstream infections (BSIs) in a tertiary-care university hospital. CRKP-related BSIs ranged from 3.7% to 9.
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- The study examined the impact of the COVID-19 pandemic on healthcare-associated infections (HAIs), antibiotic resistance, and consumption rates in ICU patients at a university hospital, comparing data from before and during the pandemic (2018-2021).
- Results indicated a higher incidence of bloodstream infections in COVID-19 ICUs during the pandemic, with significant increases in related infection rates compared to pre-pandemic times and other non-COVID ICUs.
- Antibiotic usage patterns also shifted, with notable differences in infection rates and antibiotic resistance, particularly regarding extended-spectrum beta-lactamase (ESBL) positivity rates, which were higher in the COVID-19 ICU.
Background: Blood components should be gamma-irradiated (γ-IR) in order to prevent transfusion-associated graft-versus-host disease. The aim of this study is to determine the effect of γ-IR and storage time on the exosomes released from apheresis platelet concentrates (aPC) and to investigate their impact on the maximum platelet aggregation (MPA) and hemostasis.
Materials And Methods: Eight units of aPC were included in this study.
Background: The potential role of interleukin-6 (IL-6) in coronavirus disease 2019 (COVID-19) pneumonia provides the rationale for investigating IL-6 signaling inhibitors.
Objectives: To evaluate and report treatment responses to tocilizumab (TCZ) in COVID-19 patients and compare mortality outcomes with those of standard care.
Material And Methods: Patients hospitalized with a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, diagnosed with reverse transcription polymerase chain reaction (RT-PCR) between March 2020 and April 2021, were enrolled in this single-center retrospective cohort study.