Home-based transcranial direct current stimulation treatment for major depressive disorders: Consideration from a systematic review and meta-analysis.

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Adrenomedullin 2/Intermedin Exerts Cardioprotective Effects by Regulating Cardiomyocyte Mitochondrial Function.

Background: Adrenomedullin 2 (AM2) plays critical roles in regulating blood pressure and fluid balance. However, the specific involvement of AM2 in cardiac hypertrophy has not been comprehensively elucidated, warranting further investigation into its molecular mechanisms and therapeutic implications.

Methods: Cardiac hypertrophy was induced in adult mice lacking AM2 (AM2-/-) using transverse aortic constriction surgery.

Exploring the subtle and novel renal pathological changes in diabetic nephropathy using clustering analysis with deep learning.

To decrease the number of chronic kidney disease (CKD), early diagnosis of diabetic kidney disease is required. We performed invariant information clustering (IIC)-based clustering on glomerular images obtained from nephrectomized kidneys of patients with and without diabetes. We also used visualizing techniques (gradient-weighted class activation mapping (Grad-CAM) and generative adversarial networks (GAN)) to identify the novel and early pathological changes on light microscopy in diabetic nephropathy.

Single-particle tracking of polymer aggregates inside disordered porous media.

The diffusion motions of individual polymer aggregates in disordered porous media were visualized using the single-particle tracking (SPT) method because the motions inside porous media play important roles in various fields of science and engineering. In the aggregates diffused on the surfaces of pores, continuous adsorption and desorption processes were observed. The relationship between the size of the aggregates and pore size was analysed based on diffusion coefficients, moment scaling spectrum (MSS) slope analysis, and diffusion anisotropy analysis.

Association of Systemic Inflammation with Dietary Intake, Nutrition Impact Symptoms, and Eating-Related Distress Among Patients with Advanced Cancer.

Background: Serum C-reactive protein (CRP) levels are correlated with patient outcomes in cancer. This study aimed to determine associations between the CRP level and the dietary intake, symptoms, and eating-related distress (ERD).

Methods: We conducted a multicenter survey among advanced cancer patients.