Publications by authors named "Y Gohto"
Article Synopsis
- - COVID-19 vaccines are effective at reducing disease severity, but some individuals may develop systemic rheumatic diseases post-vaccination, including giant cell arteritis (GCA).
- - A case study highlights a 73-year-old woman who experienced symptoms like headache and jaw pain shortly after her seventh COVID-19 mRNA vaccine dose, eventually leading to vision problems due to ischemic optic neuropathy.
- - The patient was diagnosed with GCA and received treatment, responding mildly to high-dose glucocorticoids and tocilizumab, which emphasizes the importance of monitoring such cases following vaccination.
Purpose: Measurements of macular pigment optical density (MPOD) using the autofluorescence spectroscopy yield underestimations of actual values in eyes with cataracts. Previously, we proposed a correction method for this error using deep learning (DL); however, the correction performance was validated through internal cross-validation. This cross-sectional study aimed to validate this approach using an external validation dataset.
View Article and Find Full Text PDFThe Veggie Meter® (VM) is a refraction spectrometer that detects skin carotenoids. We tested the variability of the two modes (single-scan and averaging modes) of four VMs of three different versions (VM-1, 2, 3, 4) with 92 healthy volunteers. Both the modes exhibited a high intra-class correlation coefficient (ICC); however, the averaging mode had a significantly lower coefficient of variance than the single-scan mode.
View Article and Find Full Text PDFThe macular pigment consisting of lutein (L) and zeaxanthin (Z) protects photoreceptors via its antioxidative and barrier activities. This study aimed to determine L and Z distribution in the healthy macula and their association with various demographic factors. Macular pigment optical density (MPOD) was measured using fundus autofluorescence spectroscopy in 352 pseudophakic eyes with no fundus diseases.
View Article and Find Full Text PDFPurpose: Measurements of macular pigment optical density (MPOD) by the autofluorescence technique yield underestimations of actual values in eyes with cataract. We applied deep learning (DL) to correct this error.
Subjects And Methods: MPOD was measured by SPECTRALIS (Heidelberg Engineering, Heidelberg, Germany) in 197 eyes before and after cataract surgery.