[Morbidity and psychomotor development at 2 years of age in children born in Puy-de-Dome in 1983. Study of children groups defined by perinatal risk].

All infants born in the Puy-de-Dôme area in 1983 and referred to a neonatal care unit were studied prospectively. Children were seen at their homes at 9 months and at 2 years of age and results were compared with those found in controls. High risk groups were defined on the basis of neonatal variables including prematurity, neurologic anomalies, respiratory distress, assisted ventilation, and growth retardation.

[Thyroid hormones during a hypocaloric diet in obese patients].

The levels of T3, RT3, T3/RT3, T4, FT4 index or T4/TBG, TSH, at days 1, 4, 8, 15 of a 800-1 000 diet with 60-80 g of carbohydrates, were studied in 45 subjects. Statistical analysis was performed using parametric and non parametric tests for comparison of the mean levels between days 1 and 4, 1 and 8, 1 and 15, 4 and 8, 4 and 15, 8 and 15. We observed no difference between men and women.

[Insulin reserve of insulin-dependent diabetics. Role of C-peptide in the hormonal balance in diabetes].

Insulin secretion was investigated in 65 insulin-dependent diabetic patients by determining C peptide levels before and after stimulation with either an 800 calories test meal or an injection of glucagon or arginine i.v. Most patients had very low basal C peptide levels and response to all stimulation tests was poor as compared to controls.

[In vitro study of the bacteriostatic and bactericidal activity of temocillin (BRL 17421)].

Temocillin is a carboxypenicillin; a methoxy group in the 6-alpha position should confer to the molecule greater stability to beta-lactamases. 236 strains isolated from clinical specimens were tested. MICs were determined by agar dilution method.