Intestinal cell apoptosis and Bcl-2 expression.

Programmed cell death (apoptosis) is a normal characteristic of cells with a limited life span like the enterocyte and the usual mode of death for proliferative crypt cells subjected to radiation or chemotherapy. The Bcl-2 proto-oncogene is considered a major regulator of apoptosis. We investigated the relationship of enterocyte apoptosis and Bcl-2 expression in rat intestine and tissue culture cells.

Squamous cell carcinoma of the stomach.

A case of pure squamous cell carcinoma of the stomach in a 72-year-old male is reported. Epidermoid carcinomas of the stomach without a glandular cell component is a rare tumor, described in only 22 patients since 1905. It occurs mostly in males, with a male to female ratio of 5:1, affects a slightly younger age group as compared to adenocarcinoma, and has a predilection for the proximal stomach, especially along the lesser curvature.

New concepts of the pathogenesis in the healing process of gunshot wounds.

By applying cytogenetic methods to the study of gunshot injuries, the authors showed that disturbances of the chromosomic apparatus integrity occurred. These disturbances are present for a long period and aggravate the severity of the wound-healing process.