Publications by authors named "Y Feodorova"
Aberrant expression of CK7/CK20/CDX2 is reported in percentage of colorectal carcinomas (CRC).
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- Scientists study unusual things to learn more about normal body processes.
- The thyroglobulin gene is really special because it stays very active for a long time in thyroid cells.
- This gene works similarly in many different animal groups and doesn't change based on hormone levels, making it a great model for research.
Colorectal carcinoma is the third most common cancer worldwide. The usual immunophenotype of colorectal adenocarcinoma is CDX2 positive, CK20 positive, and CK7 negative. Aberrant expression is reported in a variety of colorectal carcinomas but its relation to morphological variables and survival data is still unclear.
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- The text explores how transcription influences the spatial organization of the genome, particularly focusing on the structure of long, highly expressed genes.
- It describes the formation of open-ended transcription loops where polymerases move and produce RNA, challenging previous understandings of gene transcription.
- The findings indicate that these transcription loops, which resemble structures seen in certain chromosomes, suggest new insights into eukaryotic transcription mechanisms beyond the traditional model of transcription factories.
While the pharmacology of leaf extract has been studied extensively, little is known about the pharmacological potential of seeds, although they contain similar active ingredients that are responsible for the therapeutic effects of the leaf extract. In this study we used 70%-methanol kernel extract, quantified its bioactive constituents and tested their cytotoxic effect on two cancer cell lines, A2058 and HCT116, and the non-tumor cell line McCoy-Plovdiv. We studied the biological effect of the extract by real-time analysis in the xCELLigence system, WST-1 assay and LIVE/DEAD viability assay.
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