3D Mechanical Response Stem Cell Complex Repairs Spinal Cord Injury by Promoting Neurogenesis and Regulating Tissue Homeostasis.

Spinal cord injury (SCI) leads to acute tissue damage that disrupts the microenvironmental homeostasis of the spinal cord, inhibiting cell survival and function, and thereby undermining treatment efficacy. Traditional stem cell therapies have limited success in SCI, due to the difficulties in maintaining cell survival and inducing sustained differentiation into neural lineages. A new solution may arise from controlling the fate of stem cells by creating an appropriate mechanical microenvironment.

Construction of Axially Chiral Dialdehydes via Rhodium-Catalyzed Enantioselective C-H Amidation.

Achieving axially chiral biaryl dialdehydes through asymmetric catalysis remains significantly challenging due to the lack of efficient strategies. In this report, we developed a rhodium-catalyzed enantioselective C-H amidation through chiral transient directing group strategy. With this new approach, a series of axially chiral amido dialdehydes were achieved in up to 86% yields with 99.

ApWD40a, a Member of the WD40-Repeat Protein Family, Is Crucial for Fungal Development, Toxin Synthesis, and Pathogenicity in the Ginseng Alternaria Leaf Blight Fungus .

, the primary pathogen that causes ginseng Alternaria leaf blight disease, can lead to a 20-30% reduction in ginseng yield. WD40 repeat-containing proteins are evolutionarily conserved proteins with diverse functions between different organisms. In this study, we characterized the roles of a WD40 repeat-containing protein in .

Metal-Support Interactions in PdCu/NiZnP Nanohybrids Enhance Alcohol Electrooxidation.

Developing high-performance catalysts for the alcohol electrooxidation reaction is of significant importance for the practical application of direct fuel cells. Herein, a supported catalyst consisting of well-dispersive PdCu nanoparticles (NPs) and ultrathin NiZnP nanosheets (NSs) is synthesized. The high-surface-area NiZnP NSs provide a platform for good dispersion of PdCu NPs, resulting in stable catalysts with a large number of exposed surface atoms.

A dimmable LED light source along the Planckian locus.

Multiple channels are designed for dimmable LED light sources with color temperatures ranging from 2,700 to 6,500 K. However, issues such as Delta uv (D) values <0, lower brightness, luminous efficacy, and color rendering index (CRI), lower power density, exceeding the standard deviation of color matching (SDCM), unconstant power, poor color consistencies, and high costs persist. We present a three-channel LED light source featuring an integrated chip-on-board (COB) package structure.