Publications by authors named "Y Ergun"
Incorporating artificial intelligence (AI) into in vitro fertilization (IVF) laboratories signifies a significant advancement in reproductive medicine. AI technologies, such as neural networks, deep learning, and machine learning, promise to enhance quality control (QC) and quality assurance (QA) through increased accuracy, consistency, and operational efficiency. This comprehensive review examines the effects of AI on IVF laboratories, focusing on its role in automating processes such as embryo and sperm selection, optimizing clinical outcomes, and reducing human error.
View Article and Find Full Text PDFAdvancing hepatocellular carcinoma treatment with hepatic arterial infusion chemotherapy.
World J Gastrointest Oncol
December 2024
Article Synopsis
- * Hepatic arterial infusion chemotherapy (HAIC) has shown promising results in Asia for unresectable HCC, but its use is limited in Western countries despite a recent meta-analysis demonstrating its effectiveness.
- * The meta-analysis reviewed includes 9 randomized controlled trials and shows that HAIC improves overall survival and response rates, stressing the need for more research and the adoption of HAIC in Western clinical practices to enhance HCC treatment outcomes.
Article Synopsis
- The study compared the effectiveness and safety of FOLFIRI combined with bevacizumab versus FOLFIRI combined with aflibercept in patients with RAS-mutant metastatic colon cancer who had previously received treatment.
- Results showed that patients receiving FOLFIRI with bevacizumab had a median overall survival (OS) of 14.1 months and progression-free survival (PFS) of 7.7 months, which were significantly better than those treated with aflibercept (OS: 11.2 months, PFS: 5.7 months).
- Additionally, the bevacizumab group experienced fewer severe side effects (50.9% in aflibercept group vs 25.
Tryptamine, a monoamine alkaloid with an indole ring structure, is derived from the decarboxylation of the amino acid tryptophan, which is present in fungi, plants, and animals. Tryptamine analogues hold significant therapeutic potential due to their broad pharmacological activities, including roles as neurotransmitters and potential therapeutic agents for various diseases. Structural modifications of tryptamine enhance receptor selectivity and metabolic stability, improving therapeutic efficacy.
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