Publications by authors named "Y El Chazli"

Diverse bacteria can colonize the animal gut using dietary nutrients or by engaging in microbial crossfeeding interactions. Less is known about the role of host-derived nutrients in enabling gut bacterial colonization. Here we examined metabolic interactions within the evolutionary ancient symbiosis between the honey bee (Apis mellifera) and the core gut microbiota member Snodgrassella alvi.

View Article and Find Full Text PDF

The aim of this study was to assess pulmonary dysfunction in children with transfusion-dependent thalassemia (TDT) using the Global Lung Function Initiative (GLI) 2022 race-neutral spirometric reference equations and to determine the main predicting factors. The spirometric results of 68 children with TDT were compared to the results of 68 healthy control subjects using both GLI-2012 reference equations for Caucasians and GLI-2022 global equations. Associations between the spirometric data and various anthropometric, clinical, and laboratory parameters were analyzed to detect predictors of pulmonary dysfunction in this group of patients.

View Article and Find Full Text PDF

Bacteria colonize specific niches in the animal gut. However, the genetic basis of these associations is often unclear. The proteobacterium is a widely distributed gut symbiont of honey bees.

View Article and Find Full Text PDF

Social bees harbor conserved gut microbiotas that may have been acquired in a common ancestor of social bees and subsequently codiversified with their hosts. However, most of this knowledge is based on studies on the gut microbiotas of honey bees and bumblebees. Much less is known about the gut microbiotas of the third and most diverse group of social bees, the stingless bees.

View Article and Find Full Text PDF
Article Synopsis
  • Lipoid proteinosis (LP) is a rare genetic disorder caused by mutations in the ECM1 gene, leading to symptoms like hoarseness, skin lesions, and neuropsychological issues.
  • Researchers conducted clinical evaluations and genetic testing on eight patients from four unrelated Arab families, identifying two new ECM1 variants and two known variants.
  • The study highlights intrafamilial differences in patient symptoms while confirming that exon 6 is a common site for mutations in the ECM1 gene.
View Article and Find Full Text PDF