Publications by authors named "Y Eguchi"

Intracranial hemorrhage (ICH) is one of the most serious complications related to the prognosis of patients with hemophilia. It is also one of the major causes of epilepsy in general. However, there are few studies on epilepsy as a complication in patients with hemophilia.

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Aim: In the PEMA-FL study in patients with metabolic dysfunction-associated steatotic liver disease (MASLD), pemafibrate was shown to significantly decrease low-density lipoprotein cholesterol (LDL-C) levels. We aimed to investigate the mechanisms of pemafibrate-induced LDL-C reduction in patients with MASLD by conducting an additional sub-analysis of the PEMA-FL study.

Methods: The PEMA-FL study randomized 118 patients with MASLD to receive pemafibrate or placebo for 72 weeks.

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Nucleophilic aromatic substitutions (SAr) of alkoxides on pentafluoroaryl ethers are explored as a first step in a synthesis sequence to generate all- 2,3,5,6-tetrafluorocyclohexyl-1,4-dialkyl ethers . The SAr reaction was explored both experimentally and theoretically to rationalize // selectivities. -Butyl deprotection of products followed by phenol alkylations introduces versatility to the synthesis.

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Background And Aims: The clinical characteristics and risk factors involved in the development of liver fibrosis in the subtypes of steatotic liver disease (SLD) remain unknown. We examined the clinical characteristics of SLD subtypes using a large Japanese cohort.

Methods: We performed a cross-sectional analysis (total n = 108,446).

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Recent studies have revealed that biotic interactions in ecological communities vary over time, possibly mediating community responses to anthropogenic disturbances. This study investigated the heterogeneity of such variability within a real community and its impact on population stability in the face of pesticide application, particularly focusing on density-dependence of the interaction effect. Using outdoor mesocosms with a freshwater community, we found considerable heterogeneity in density-dependent interaction variability among links in the same community.

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