Hook plate fixation and tension band wiring in the treatment of Mayo type II olecranon fractures.

Background: Olecranon fractures account for 8 ∼ 10% of all elbow fractures and usually require surgical intervention. Tension band wiring (TBW) is considered as the standard treatment while it is associated with high re-operation rates.

Objective: This study aims to compare the functional outcomes, complications and re-operations of hook plate fixation (HPF) versus TBW in treating Mayo Type II olecranon fractures.

Integrative genomic analysis of DLBCL identifies immune environments associated with bispecific antibody response.

Most diffuse large B-cell lymphoma (DLBCL) patients treated with immunotherapies such as bispecific antibodies (BsAb) or chimeric antigen receptor (CAR) T cells fail to achieve durable treatment responses, underscoring the need for a deeper understanding of mechanisms that regulate the immune environment and response to treatment. Here, an integrative, multi-omic approach was applied to multiple large independent datasets in order to characterize DLBCL immune environments, and to define their association with tumor cell-intrinsic genomic alterations and outcomes to CD19-directed CAR T-cell and CD20 x CD3 BsAb therapies. This approach effectively segregated DLBCLs into four immune quadrants (IQ) defined by cell-of-origin and immune-related gene set expression scores.

Development and Evaluation of an Immunochromatographic Strip and a Magnetic Chemiluminescence Immunoassay for Detection of Antigen.

(PCV2) is the main and primary causative agent of Postweaning Multisystemic Wasting Syndrome (PMWS). To date, immunoperoxidase monolayer assay (IPMA), indirect immunofluorescent assay (IFA), and enzyme linked immunosorbent assay (ELISA) are the most commonly diagnostic methods for detecting PCV2 antigens. However, these methods require specialized equipment and technical expertise and are suitable for laboratory use only.

Effects of Supplementation With Different Specificities of Dietary Fiber on Health-Related Indicators in Adults With Overweight or Obesity: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Context: Dietary fiber (DF) exhibits variations in its chemical and physical complexity, as well as in its utilization by the gut microbiota. However, the impact of these differences on the health status of adults with overweight or obesity remains unclear.

Objective: This meta-analysis aimed to explore the varying effects of supplementing with different specificities of DF on the health of adults with overweight or obesity, providing guidance on selecting DF supplementation to improve health status.

Phanerochaete chrysosporium hyphae bio-crack, endocytose and metabolize plastic films.

Numerous studies have focused on the effect and mechanism of plastic degradation; due to their high persistence, petroleum-based plastics are difficult for microbes to mineralize. Although such plastics have been demonstrated to be mineralized by white rot fungus, the reactions at the molecular level remain unknown. Here, we show the whole mineralization model of polyethylene film, that can be summarized as follows: 1) white rot fungus colonizes on polyethylene film, using additives as dissimilated carbon sources; 2) the fungus secretes extracellular enzymes protein, combining with stearic acid as electron donor, causes oxidation and cracking of polyethylene film; and 3) partial dissociated sub-microplastic debris access to cells, further oxidizes in sequential actions of intracellular enzymes, and ultimately mineralize via β-oxidation.