Publications by authors named "Y E Vaucher"
Article Synopsis
- The study aimed to see if neonatal complications were linked to death or severe neurodevelopmental impairment in extremely preterm infants who lived to 36 weeks.
- It analyzed data from nearly 3,800 infants born between 22 and 26 weeks gestation at 15 research centers, finding that serious brain injury, bronchopulmonary dysplasia, and severe retinopathy were the most significant risks.
- A higher count of these morbidities correlated with increased rates of death or severe neurodevelopmental impairment, with rates jumping from 12.6% for no morbidities to 69.9% for all three.
Article Synopsis
- This case series investigates whether preterm infants with a gestational age of 32 weeks or more and a birth weight over 1500 grams should be screened for retinopathy of prematurity (ROP) earlier than current guidelines.
- At St. Francis Hospital in Uganda, 3 infants required treatment for severe ROP before 30 days of life after receiving unblended oxygen for several days.
- The findings suggest that infants in this category may be at a higher risk of developing severe ROP sooner than previously recommended by existing guidelines.
Background: To address the threat of retinopathy of prematurity (ROP) in Sub-Saharan Africa (SSA), the Stop Infant Blindness in Africa (SIBA) project introduced a comprehensive program, including subspecialty training and oxygen management equipment.
Methods: A before-and-after retrospective cohort study compared preterm infants < 1750 g or < 34 weeks' gestation before (2022) and after (2023) program implementation. Outcomes included: the proportion with severe ROP, the proportion with Zone III vascularization on first examination, and factors associated with severe ROP.
Importance: Compared with early cord clamping (ECC), umbilical cord milking (UCM) reduces delivery room cardiorespiratory support, hypoxic-ischemic encephalopathy, and therapeutic hypothermia in nonvigorous near-term and full-term infants. However, UCM postdischarge outcomes are not known.
Objective: To determine the 2-year outcomes of children randomized to UCM or ECC at birth in the Milking in Nonvigorous Infants (MINVI) trial.
Objectives: To determine whether rate of severe intraventricular hemorrhage (IVH) or death among preterm infants receiving placental transfusion with UCM is noninferior to delayed cord clamping (DCC).
Methods: Noninferiority randomized controlled trial comparing UCM versus DCC in preterm infants born 28 to 32 weeks recruited between June 2017 through September 2022 from 19 university and private medical centers in 4 countries. The primary outcome was Grade III/IV IVH or death evaluated at a 1% noninferiority margin.