Case report: A successful case of targeted immunotherapy for locally advanced pancreatic cancer under non-surgical conditions.

Introduction: Locally advanced pancreatic cancer (LAPC) is a borderline unresectable malignancy that presents significant treatment challenges. The management of LAPC remains a complex issue, particularly in patients who are not eligible for surgical resection.

Case: Here, we report the case of a 60-year-old woman diagnosed with LAPC through pathological biopsy who subsequently underwent targeted immunotherapy following the failure of a gemcitabine, oxaliplatin, and S-1 (G&S) chemotherapy regimen.

Comparison of three different in vitro digestion methods for carbohydrates.

Spectrophotometer method, ELISA, and High-performance anion exchange chromatography with pulsed amperometric detection (HPAEC-PAD) method have been widely used to quantify and characterize the glucose released from rice after in vitro digestion. Despite this, the results of the three methods may not be comparable. This work investigated the limitation of detection (LOD) and quantification (LOQ) of the glucose released after in vitro rice digestion.

Associations of Urinary Perchlorate, Nitrate, and Thiocyanate with Female Infertility and Mediation of Obesity: Insights from NHANES 2013-2018.

Classified as endocrine disrupting chemicals (EDCs), perchlorate, nitrate, and thiocyanate have been implicated with obesity and reproductive disorders. This study used three cycles of the National Health and Nutrition Examination Survey (NHANES 2013-2018); 813 women of reproductive age were finally included. We used multivariable logistic regression to analyze the associations between the three anions and obesity and infertility.

Storage stability evaluation of chicken seasoning by accelerating oil oxidation under different storage conditions.

The effects of temperature, humidity, and UV irradiation on the accelerated oil oxidation of chicken seasoning (CS) were investigated, aiming to establish a method for evaluating its storage stability. Key oxidation indicators, such as peroxide value (POV), fatty acid profile, and volatile aldehydes, were measured to assess the degree of oil oxidation. The results indicated that oil oxidation of CS is not significantly accelerated by temperatures of 50-80 °C due to the inhibitory effects of the Maillard reaction.

Protein hydrogel formation from chicken processing By-Products: Exploring applications in food.

Chicken processing by-products, such as meat left over on bones, skin, frames and connective tissues, are great sources of functional proteins that offer significant potential for value-added applications, contributing to both waste reduction and environmental sustainability. By transforming the recovered proteins from by-products into hydrogels, new materials can be developed for use in various industries, including food. However, understanding the chemical composition of these by-products and optimizing hydrogel production techniques are critical to producing hydrogels with desirable properties.