Experimental morphological analysis of surgical bypassing of the uveal tract.

Histological preparations of eyeball membranes from rabbits subjected to decompression multisclerectomy providing alternative drainage pathway were examined. The procedure was performed with or without application of a 5-fluorouracil-impregnated implant. The use of this implant always resulted in the formation of relatively wide endothelialized transscleral channels and ensured their persistence in the late postoperation period.

Surgical stimulation of the uveoscleral outflow. Experimental studies on enucleated human eyes.

Six series of experiments were performed on 45 isolated cadaver eyes. In the first series, the outflow facility of the human sclera was measured, in the others, five surgical techniques for stimulating the uveo-scleral outflow were evaluted with the help of a constant pressure perfusion technique. It was found that the scleral C-value was pressure independent and its average value was equal to 0.