Publications by authors named "Y Dror"
Article Synopsis
- * It highlights recent findings on antimony trichalcogenide and chalcohalide materials, which can recover from photoinduced damage through a reversible phase transition, providing a basis for studying their unique properties.
- * The study reveals that as bismuth replaces antimony in these materials, the ability to recover from damage decreases, stressing the importance of specific bonding characteristics for effective self-healing in semiconductors.
Mutations in the DNAJC21 gene were recently described in Shwachman-Diamond syndrome (SDS), a bone marrow failure syndrome with high predisposition for myeloid malignancies. To study the underlying biology in hematopoiesis regulation and disease, we generated the first in vivo model of Dnajc21 deficiency using the zebrafish. Zebrafish dnajc21 mutants phenocopy key SDS patient phenotypes such as cytopenia, reduced growth, and defective protein synthesis.
View Article and Find Full Text PDFShwachman-Diamond syndrome (SDS) is an inherited bone marrow failure disorder that often presents at infancy. Progress has been made in revealing causal mutated genes (SBDS and others), ribosome defects, and hematopoietic aberrations in SDS. However, the mechanism underlying the hematopoietic failure remained unknown, and treatment options are limited.
View Article and Find Full Text PDFArticle Synopsis
- Severe aplastic anemia (SAA) is a rare and serious blood disorder that can be life-threatening.
- Treatment outcomes are generally positive, but there are differences in how SAA is managed in adults versus children, and ongoing clinical trials are exploring various treatment options.
- Due to its rarity, some pediatric hematologists may lack extensive experience in treating SAA, highlighting the importance of current evidence-based recommendations for managing children with relapsed or refractory cases.
Article Synopsis
- Severe aplastic anemia (SAA) is a rare but serious blood disorder that can be life-threatening.
- Treatment for SAA works well, but how it's handled can be different for kids and adults.
- Some doctors who treat children may not have a lot of experience with SAA since it's so rare, so there are new recommendations to help them.