Publications by authors named "Y Delgado"
Objective: Currently, in Puerto Rico (PR) there is no study for HPV vaccination rates after implementing mandatory HPV vaccination school entry policy in 2018. This study aims to (a) explore HPV vaccination status in adults (≥18 years) residing in PR., particularly those who fall within the age range approved for vaccination; (b) describe participants' gender and sexual identities and behavior risk factors; and (c) determine how the willingness to vaccinate against HPV is influenced by sociodemographic factors such as age, gender, education level, and health insurance.
View Article and Find Full Text PDFArticle Synopsis
- * The text describes a specific proteomics method called affinity purification-mass spectrometry (AP-MS) to study protein interactions by tagging "bait" proteins in mammalian cells.
- * This protocol allows researchers to identify, quantify, and visualize changes in protein-protein interaction networks under different conditions and is adaptable across various cell types and biological studies.
Clinically approved iron chelators, originally designed to address iron overload disorders, have emerged as potential anticancer agents. Deferasirox (Def), a tridentate iron chelator, has demonstrated antiproliferative effects in cancer. : This study aims to elucidate the mechanism of action of Def and its impact on non-small cell lung carcinoma (NSCLC).
View Article and Find Full Text PDFRecently, there has been great interest in plant-derived compounds known as phytochemicals. The pentacyclic oleanane-, ursane-, and lupane-type triterpenes are phytochemicals that exert significant activity against diseases like cancer. Lung cancer is the leading cause of cancer-related death worldwide.
View Article and Find Full Text PDFBackground: Given the pervasive issues of obesity and diabetes both in Puerto Rico and the broader United States, there is a compelling need to investigate the intricate interplay among BMI, pregestational, and gestational maternal diabetes, and their potential impact on the occurrence of congenital heart defects (CHD) during neonatal development.
Methods: Using the comprehensive System of Vigilance and Surveillance of Congenital Defects in Puerto Rico, we conducted a focused analysis on neonates diagnosed with CHD between 2016 and 2020. Our assessment encompassed a range of variables, including maternal age, gestational age, BMI, pregestational diabetes, gestational diabetes, hypertension, history of abortion, and presence of preeclampsia.