L-arginine attenuates dichlorvos-induced testicular toxicity in male Wistar rats by suppressing oxidative stress-dependent activation of caspase 3-mediated apoptosis.

Background: The continuous use of pesticides, such as dichlorvos, is a common agricultural and domestic practice. However, it is associated with shortfalls like testicular toxicity through the induction of oxidative stress-mediated signaling. On the other hand, L-arginine, a precursor of nitric oxide, has been reported to exert antioxidant activities and thus may attenuate dichlorvos-induced testicular toxicity.

Anti-hyperlipidemic and antioxidant potentials of aqueous leaf extract of Telfairia occidentalis (fluted pumpkin) in male Sprague-Dawley rats.

In Africa traditional medicine, certain plant leaves are employed in the treatment of metabolic disorders such as dyslipidaemia. Telfairia occidentalis is named among Nigerian plants that are under investigation for anti-hyperlipidemic activity. The antihperlipidemic and antioxidant potentials of Telfairia Occidentalis (TO) aqueous leaf extract were studied in male Sprague- Dawley rats.