Negative association between 15 obesity- and lipid-related indices and testosterone in adult males: a population based cross-sectional study.

Background: An association exists between obesity and reduced testosterone levels in males. The propose of this research is to reveal the correlation between 15 indices linked to obesity and lipid levels with the concentration of serum testosterone, and incidence of testosterone deficiency (TD) among adult American men.

Methods: The study utilized information gathered from the National Health and Nutrition Examination Survey (NHANES) carried out from 2011 to 2016.

Quasi-vertically asymmetric channels of graphene oxide membrane for ultrafast ion sieving.

The high performance of two-dimensional (2D) channel membranes is generally achieved by preparing ultrathin or forming short channels with less tortuous transport through self-assembly of small flakes, demonstrating potential for highly efficient water desalination and purification, gas and ion separation, and organic solvent waste treatment. Here, we report the construction of vertical channels in graphene oxide (GO) membrane based on a substrate template with asymmetric pores. The membranes achieved water permeance of 2647 L m h bar while still maintaining an ultrahigh rejection rate of 99.

Path analysis of factors influencing length of stay and hospitalisation expenses for oral cancer patients in tertiary hospitals in southeastern China: a cross-sectional study.

Aims: To investigate the associations between influencing factors with length of stay (LOS) and hospitalisation expenses in oral cancer (OC) patients, and to explore the potential pathways through which these factors influence hospitalisation expenses using path analysis.

Design: Cross-sectional.

Setting: A comprehensive tertiary hospital in southeastern China.

Dual targeting PPARα and NPC1L1 metabolic vulnerabilities blocks tumorigenesis.

Dysregulated lipid metabolism is linked to tumor progression. In this study, we identified Niemann-Pick C1-like 1 (NPC1L1) as a downstream effector of PKM2. In breast cancer cells, PKM2 knockout (KO) enhanced NPC1L1 expression while downregulating peroxisome proliferator-activated receptor α (PPARα) signaling pathway.

Heterotrophic denitrification enhancement via effective organic matter degradation driven by suitable iron dosage in sediment.

The control of internal pollution was important throughout the restoration of the lake, especially the removal of sediment internal nitrogen. Experiments involving incubation were conducted in this study to investigate the effects of iron remediation on nitrogen in both water and sediment. Adding iron with varying dosage had different effects on the nutrients content and other properties of water and sediment in remediation.