Publications by authors named "Y Chia"

As dementia has been declared a global health crisis by the World Health Organization, this perspective paper aims to shed light on the cuerent stata of dementia care in Malaysia. The paper firsc outlinea eeveral barriers to dementia care in Malaysia. The shortage of geriatric specialists hampers the accessibility of dementia caee avd resceerces.

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Background: Palbociclib plus an aromatase inhibitor is approved for treatment of patients with ER+/HER2- advanced breast cancer (ABC). In the PALOMA-4 trial, adding palbociclib to letrozole prolonged median progression-free survival in Asian women with ER+/HER2- ABC. Here, we report patient-reported outcomes (PROs) from PALOMA-4.

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Article Synopsis
  • - The study examines how aging affects cognition and brain structure in older adults, focusing on individual differences and the impact of sociodemographic factors on cognitive decline.
  • - Researchers analyzed a group of Southeast-Asian older adults through cognitive tests, brain imaging, and interviews to identify cognitive profiles and how they relate to brain health and socioeconomic status.
  • - Findings revealed that specific cognitive impairments were linked to reductions in brain regions related to cognitive control and that lower socioeconomic standing and cognitive reserve contributed to poorer cognitive performance, highlighting the complex relationship between aging, brain health, and social factors.
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Cardiovascular diseases (CVD) continue to be the leading cause of deaths and disability worldwide and the major contributor is hypertension. Despite all the improvements in detecting hypertension together with technological advances and affordable, efficacious and relatively free of adverse effects anti-hypertensive agents, we continue to struggle to prevent the onset of hypertension and to control blood pressure (BP) to acceptable targets. The poor control of hypertension is commonly due to non-adherence to medications.

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