Effect of single-unit transfusion in patients treated for haematological disease including acute leukemia: A multicenter randomized controlled clinical trial.

Background: Retrospective studies in hematological unit have suggested that single red blood cell (1-RBC) unit transfusion policy may reduce the number of RBC used without negative clinical impact.

Method: Acute leukemia patients requiring intensive chemotherapy or patients receiving autologous or allogeneic transplantation were randomly assigned to receive either single RBC (1-RBC arm) or double RBC (2-RBC arm) per transfusion with a hemoglobin trigger of 8 g/dL. The primary composite endpoint was the percentage of patients experiencing serious complications, such as a non-hematological adverse event grade ≥ 3 or intensive care admission or death.

'French LARS score': validation of the French version of the low anterior resection syndrome (LARS) score for measuring bowel dysfunction after sphincter-preserving surgery among rectal cancer patients: a study protocol.

Introduction: Many bowel problems following low anterior resection (LAR) for rectal cancer considerably impair the quality of life (QoL) of patients. The LAR syndrome (LARS) scale is a self-report questionnaire to identify and assess bowel dysfunction after rectal cancer surgery. It has been translated and validated in several languages but not in French (metropolitan French).

Multiscale imaging of plants: current approaches and challenges.

We review a set of recent multiscale imaging techniques, producing high-resolution images of interest for plant sciences. These techniques are promising because they match the multiscale structure of plants. However, the use of such high-resolution images is challenging in the perspective of their application to high-throughput phenotyping on large populations of plants, because of the memory cost for their data storage and the computational cost for their processing to extract information.

Patient satisfaction with language--concordant care.

Purpose: The Spanish-speaking Hispanic patient population is more likely to be in poor health than their English-speaking counterparts. These patients are less satisfied with their care, which may lead to adverse health outcomes.

Methods: A quantitative, descriptive study was conducted in San Bernardino, California.

Maggot therapy for wound debridement: a randomized multicenter trial.

Objective: To study the efficacy of bagged larvae on wound debridement compared with conventional treatment.

Design: Randomized, multicenter, controlled, prospective phase 3 trial with blinded assessment of outcome measures by a single observer.

Setting: Two hospital referral centers in Caen and Lyon, France.