Publications by authors named "Y Caspar"
Tularemia is a re-emerging zoonosis in many endemic countries. It is caused by , a gram-negative bacterium and biological threat agent. Humans are infected from the wild animal reservoir, the environmental reservoir or by the bite of arthropod vectors.
View Article and Find Full Text PDFTularemia in Pediatric Patients: A Case Series and Review of the Literature.
Pediatr Infect Dis J
September 2024
Article Synopsis
- Tularemia is often misdiagnosed in children due to its similar symptoms to other common lymphadenopathy diseases, leading to delayed treatment; awareness among pediatricians is crucial.
- A review of 94 cases revealed a wide age range of affected children, with infection sources primarily from zoonotic transmission and contaminated water, and fever being a common symptom.
- Effective treatment typically includes aminoglycosides, fluoroquinolones, or tetracyclines, and pediatricians should consider tularemia in cases of febrile lymphadenopathy to avoid unnecessary costs from misguided antibiotic treatments and extended hospital stays.
Objectives: Clinical microbiologists require easy-to-use open access tools with graphical interfaces to perform bacterial whole-genome sequencing (WGS) in routine practice. This study aimed to build a bioinformatics pipeline on the open-source Galaxy platform, facilitating comprehensive and reproducible analysis of bacterial WGS data in a few steps. We then used it to characterize our local epidemiology of ESBL-producing Enterobacterales isolated from patients with bacteremia.
View Article and Find Full Text PDFArticle Synopsis
- Francisella tularensis endocarditis is a rare infection that's tough to diagnose, with only a handful of cases documented.* -
- The report discusses two new cases caused by the subsp. holarctica strain, highlighting their positive outcomes through antibiotic treatment and valve replacement surgery.* -
- Effective treatment typically involves ciprofloxacin and gentamicin, alongside surgical intervention when required, with suspicion of the infection guided by local epidemiology and patient exposure.*