Publications by authors named "Y Cag"

Article Synopsis
  • * Researchers collected 1,346 nasopharyngeal swab samples, isolating 879 high-quality genomes for analysis, focusing on clades, lineages, age-related associations, and mutations over a 10-month period.
  • * Specific variants like B.1.1.7 (Alpha) and B.1.617.2 (Delta) were identified, along with unique mutations linked to the later Omicron variant, emphasizing the need for ongoing genetic monitoring to improve COVID-19 prevention strategies.
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Introduction: Coronavirus disease 2019 (COVID-19) has caused many injuries and deaths worldwide. Obesity is reported to be an important risk factor for severe COVID-19, although the underlying mechanism is not fully understood. The present study aimed to determine whether obesity or being overweight is associated with the clinical course and severity of COVID-19 in children.

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Article Synopsis
  • Antiseizure medications (ASMs) like levetiracetam and valproic acid may cause psychiatric side effects, including increased anger, ADHD symptoms, and oppositional defiant disorder (ODD) in children and adolescents with epilepsy.
  • * This study aimed to analyze how these two medications affect behavioral and emotional changes in young patients over a 6-month period, using structured psychiatric assessments.
  • * Results revealed that both medications significantly increased ADHD symptoms after treatment, highlighting the need for careful drug selection to minimize psychiatric issues during epilepsy treatment.
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FCH domain only 1 (FCHO1) is a key player in clathrin-mediated endocytosis, vital for various cellular processes, including immune regulation and cancer progression. However, the clinical implications of FCHO1 mutations, particularly in combined immunodeficiency, remain unclear. This systematic review aims to provide an objective analysis of the molecular genetics, clinical manifestations, and potential therapeutic targets associated with FCHO1 mutations.

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Article Synopsis
  • - Childhood obesity is linked to serious health issues, including Pseudotumor cerebri (PTC), and this study aimed to explore the relationship between body mass index (BMI) and cerebrospinal fluid (CSF) pressure in children with PTC.
  • - The study involved 48 children under 18 diagnosed with PTC, revealing that 41.67% were overweight or obese, and those with higher BMI had increased CSF pressure compared to those with normal BMI.
  • - Findings suggest a direct correlation between CSF pressure and BMI, highlighting the importance of diet and exercise in managing PTC, along with a relationship between CSF pressure and monocyte levels.
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