Evidence based QUality Improvement for Prescribing Stewardship in ICU (EQUIPS-ICU): protocol for type III hybrid implementation-effectiveness study.

Background: Approximately half of all antimicrobial prescriptions in intensive care units (ICUs) may be inappropriate, including those prescribed when not needed, in unnecessary combinations or for longer durations than needed. Inappropriate prescribing is costly, exposes patients to unnecessary side-effects and drives population-level antimicrobial resistance, the prevalence and consequences of which are greatest in low- and middle-income countries. However, the implementation of interventions to improve the appropriateness of antimicrobial prescribing has been variable and requires further study.

Mixed methods study protocol for combining stakeholder-led rapid evaluation with near real-time continuous registry data to facilitate evaluations of quality of care in intensive care units.

Background: Improved access to healthcare in low- and middle-income countries (LMICs) has not equated to improved health outcomes. Absence or unsustained quality of care is partly to blame. Improving outcomes in intensive care units (ICUs) requires delivery of complex interventions by multiple specialties working in concert, and the simultaneous prevention of avoidable harms associated with the illness and the treatment interventions.

Density structure of the Sgr B2 molecular cloud probed by low-J lines of CS.

We have observed the CS (2-1) and (3-2), and 13CS (2-1) transitions toward the Galactic Center molecular cloud Sgr B2 which consists of several clumps with different chemical properties. We have newly identified a cloud at 30 km s-1 from a CS (2-1) optical depth map. This cloud lies 1.

Are clouds collapsing at the 2' north position of Sagittarius B2?

The 3 mm lines of HCO2+ and HNCO have been observed toward Sgr B2. Besides the well-known "principal cloud" and an extended envelope, we find another gas cloud 2' north of Sgr B2(M). This 2' north (2' N) cloud which may be located behind the principal cloud, has a total mass of approximately 10(5) Msolar and a diameter of approximately 7 pc.