Predictors of parent-child bonding and parenting satisfaction during the perinatal period: A structural equation model.

Objectives: To examine the predictors of parent-child bonding and parenting satisfaction using structural equation models at three time points across the perinatal period: (1) during pregnancy at >24 gestational weeks, (2) one month postpartum, and (3) three months postpartum.

Methods: This longitudinal exploratory quantitative study recruited a convenient sample of 118 heterosexual couples (236 participants; 118 mothers and 118 fathers) from maternity clinics of a public tertiary hospital in Singapore. Descriptive statistics were used to summarize the parents' characteristics and study variables.

Unraveling the potential mechanism and prognostic value of pentose phosphate pathway in hepatocellular carcinoma: a comprehensive analysis integrating bulk transcriptomics and single-cell sequencing data.

Hepatocellular carcinoma (HCC) remains a malignant and life-threatening tumor with an extremely poor prognosis, posing a significant global health challenge. Despite the continuous emergence of novel therapeutic agents, patients exhibit substantial heterogeneity in their responses to anti-tumor drugs and overall prognosis. The pentose phosphate pathway (PPP) is highly activated in various tumor cells and plays a pivotal role in tumor metabolic reprogramming.

Advances in Whole Genome Sequencing: Methods, Tools, and Applications in Population Genomics.

With the rapid advancement of high-throughput sequencing technologies, whole genome sequencing (WGS) has emerged as a crucial tool for studying genetic variation and population structure. Utilizing population genomics tools to analyze resequencing data allows for the effective integration of selection signals with population history, precise estimation of effective population size, historical population trends, and structural insights, along with the identification of specific genetic loci and variations. This paper reviews current whole genome sequencing technologies, detailing primary research methods, relevant software, and their advantages and limitations within population genomics.

Torsion of Extralobar Pulmonary Sequestration Presenting as Posterior Mediastinal Mass.

Torsion of extralobar pulmonary sequestration is a rare congenital anomalous condition that can manifest with various symptoms, including abdominal pain. However, a masslike lesion in the mediastinum can be easily overlooked when the clinician focuses only on abdominal pain. By using magnetic resonance imaging, a few features specific to the torsion of extralobar pulmonary sequestration can be identified, and that information will be helpful.