Antifouling and Bactericidal Zwitterionic Polymer Coatings with Synergistic Inhibitory and Killing Properties.

Polymeric coatings that combine resistance to adhesion ("defending") and killing ("attacking") of biocontaminants were proposed to endow the surface with nonadhesive and bactericidal capabilities. In contrast, a zwitterionic copolymer P(GMA--DMAPS) with antifouling groups ([2-(methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide, DMAPS) and a zwitterionic/cationic copolymer P(GMA--DMAPS--DMC) with bactericidal groups ([2-(methacryloyloxy)ethyl]trimethylammonium chloride, DMC) were synthesized, of which the latter exhibited synergistic inhibitory and killing properties. The distinct feed ratios of monomers were conducted, and the optimal molar ratio was obtained.

Interplay of Weight Status and Sleep Autonomic Function in Mediating and Moderating the Link Between Disease Severity and Blood Pressure in Paediatric Obstructive Sleep Apnoea.

Introduction: Obstructive sleep apnoea (OSA) in children is associated with numerous adverse outcomes, including elevated blood pressure. While the associations between OSA, obesity, and autonomic dysfunction are recognised, the precise mechanisms linking these factors and their relationship with elevated blood pressure in children remain unclear.

Methods: This retrospective case series included 76 children with OSA.

Revisiting Dipole-Induced Fluorinated-Anion Decomposition Reaction for Promoting a LiF-Rich Interphase in Lithium-Metal Batteries.

Building anion-derived solid electrolyte interphase (SEI) with enriched LiF is considered the most promising strategy to address inferior safety features and poor cyclability of lithium-metal batteries (LMBs). Herein, we discover that, instead of direct electron transfer from surface polar groups to bis(trifluoromethanesulfonyl)imide (TFSI) for inducing a LiF-rich SEI, the dipole-induced fluorinated-anion decomposition reaction begins with the adsorption of Li ions and is highly dependent on their mobility on the polar surface. To demonstrate this, a single-layer graphdiyne on MXene (sGDY@MXene) heterostructure has been successfully fabricated and integrated into polypropylene separators.

Within-host evolution of a transcriptional regulator contributes to the establishment of chronic Pseudomonas aeruginosa infection.

As an opportunistic pathogen, Pseudomonas aeruginosa can cause both acute and chronic infections that are notoriously difficult to treat. However, the mechanism underlying acute or chronic P. aeruginosa infection remains unclear.